BDBM15234 (1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-6,11,16-trioxo-13,17-dioxapentacyclo[10.6.1.0^{2,10}.0^{5,9}.0^{15,19}]nonadeca-2(10),12(19),14-trien-3-yl acetate::CHEMBL428496::NSC221019::Wortmannin::Wortmannin, Wm::cid_312145

SMILES: COC[C@H]1OC(=O)c2coc3c2[C@@]1(C)C1=C([C@@H]2CCC(=O)[C@@]2(C)C[C@H]1OC(C)=O)C3=O

InChI Key: InChIKey=QDLHCMPXEPAAMD-UHFFFAOYSA-N

Data: 7 KI  49 IC50  5 Kd  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 64 hits for monomerid = 15234   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.20	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase alpha (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Rat)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK3 (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK3 (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK3 (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Chicken)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase type 2-alpha (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11.9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 3 (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform/Phosphoinositide 3-kinase regulatory subunit 5 (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	7.4	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	55	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	103	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	99	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.47E+8	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Endoribonuclease toxin MazF (Escherichia coli (strain K12))	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>9.90E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Endoribonuclease toxin MazF (Escherichia coli (strain K12))	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>9.90E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Endothelial PAS domain-containing protein 1 (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 2 (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.61E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 4 (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM15234 (NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair