BDBM175980 US10047103, 13::US9688695, 13

SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3nc(sc3C)-c3ccccc3)cc(OC)cc2o1

InChI Key InChIKey=BJTAAMSDIFAXOX-UHFFFAOYSA-N

Data  2 EC50

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 175980   

TargetProteinase-activated receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Co.

US Patent
LigandPNGBDBM175980(US10047103, 13 | US9688695, 13)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3nc(sc3C)-c3ccccc3)cc(OC)cc2o1
Show InChI InChI=1S/C25H20N4O4S2/c1-14-19(26-23(34-14)15-7-5-4-6-8-15)13-32-20-9-16(30-2)10-21-17(20)11-22(33-21)18-12-29-24(27-18)35-25(28-29)31-3/h4-12H,13H2,1-3H3
Affinity DataEC50:  2.10nMT: 2°CAssay Description:Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Co.

US Patent
LigandPNGBDBM175980(US10047103, 13 | US9688695, 13)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3nc(sc3C)-c3ccccc3)cc(OC)cc2o1
Show InChI InChI=1S/C25H20N4O4S2/c1-14-19(26-23(34-14)15-7-5-4-6-8-15)13-32-20-9-16(30-2)10-21-17(20)11-22(33-21)18-12-29-24(27-18)35-25(28-29)31-3/h4-12H,13H2,1-3H3
Affinity DataEC50:  2.10nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid