BDBM249396 US10537571, Compound 108::US10562888, Compound 108::US10654836, The compound of example 108 of WO2015057938::US10912774, Compound 108::US11001572, Example 108 of WO2015057938::US9434697, 108::US9730931, Compound 108

SMILES: CCN1CCN(CC1)c1ccc(Nc2cc(ncn2)N(C)C(=O)Nc2c(Cl)c(OC)cc(OC)c2Cl)c(NC(=O)C=C)c1

InChI Key: InChIKey=MBWRLLRCTIYXDW-UHFFFAOYSA-N

Data: 56 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 56 hits for monomerid = 249396   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 3 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	575	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	579	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	575	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	173	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	173	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	513	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	579	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<0.200	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	173	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	173	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	513	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	173	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.98E+3	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	173	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	513	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	173	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	173	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Human)	BDBM249396 (US9434697, 108 | US9730931, Compound 108 | US10537...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair