BDBM25899 7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide::Diulo::Metolazone::Microx::Zaroxolyn

SMILES: CC1Nc2cc(Cl)c(cc2C(=O)N1c1ccccc1C)S(N)(=O)=O

InChI Key: InChIKey=AQCHWTWZEMGIFD-UHFFFAOYSA-N

Data: 15 KI  2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 25899   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 3 (Human)	BDBM25899 (7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM25899 (7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 7 (Human)	BDBM25899 (7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 7 (Human)	BDBM25899 (7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 12 (Human)	BDBM25899 (7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 13 (Mouse)	BDBM25899 (7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 4 (Human)	BDBM25899 (7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		216	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 5B, mitochondrial (Human)	BDBM25899 (7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		312	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 9 (Human)	BDBM25899 (7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 5A, mitochondrial (Human)	BDBM25899 (7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		750	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 6 (Human)	BDBM25899 (7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		1.71E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM25899 (7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM25899 (7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		2.00E+3	-7.77	n/a	n/a	n/a	n/a	n/a	7.4	25
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Carbonic anhydrase 14 (Human)	BDBM25899 (7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		5.43E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 1 (Human)	BDBM25899 (7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		5.40E+4	-5.82	n/a	n/a	n/a	n/a	n/a	7.4	25
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Carbonic anhydrase 3 (Human)	BDBM25899 (7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.00E+5	>-5.04	n/a	n/a	n/a	n/a	n/a	7.4	25
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Carbonic anhydrase 3 (Human)	BDBM25899 (7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		6.10E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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