BDBM27452 5-(5,6-dimethoxy-1H-1,3-benzodiazol-1-yl)-3-[(2-methanesulfonylphenyl)methoxy]thiophene-2-carbonitrile::benzimidazole-thiophene carbonitrile, 12e

SMILES: COc1cc2ncn(-c3cc(OCc4ccccc4S(C)(=O)=O)c(s3)C#N)c2cc1OC

InChI Key: InChIKey=LDTAHRLHGHFHKP-UHFFFAOYSA-N

Data: 9 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 27452   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inhibitor of nuclear factor kappa-B kinase subunit epsilon (Human)	BDBM27452 (5-(5,6-dimethoxy-1H-1,3-benzodiazol-1-yl)-3-[(2-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	7.4	22
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Inhibitor of nuclear factor kappa-B kinase subunit beta (Human)	BDBM27452 (5-(5,6-dimethoxy-1H-1,3-benzodiazol-1-yl)-3-[(2-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.58E+4	n/a	n/a	n/a	n/a	7.4	22
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Serine/threonine-protein kinase PLK1 (Human)	BDBM27452 (5-(5,6-dimethoxy-1H-1,3-benzodiazol-1-yl)-3-[(2-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	794	n/a	n/a	n/a	n/a	7.2	22
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Inhibitor of nuclear factor kappa-B kinase subunit alpha (Human)	BDBM27452 (5-(5,6-dimethoxy-1H-1,3-benzodiazol-1-yl)-3-[(2-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.58E+4	n/a	n/a	n/a	n/a	7.4	22
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Aurora kinase B (Human)	BDBM27452 (5-(5,6-dimethoxy-1H-1,3-benzodiazol-1-yl)-3-[(2-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2 (Human)	BDBM27452 (5-(5,6-dimethoxy-1H-1,3-benzodiazol-1-yl)-3-[(2-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Inhibitor of nuclear factor kappa-B kinase subunit epsilon (Human)	BDBM27452 (5-(5,6-dimethoxy-1H-1,3-benzodiazol-1-yl)-3-[(2-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	469	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase TBK1 (Human)	BDBM27452 (5-(5,6-dimethoxy-1H-1,3-benzodiazol-1-yl)-3-[(2-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TBK1 (Human)	BDBM27452 (5-(5,6-dimethoxy-1H-1,3-benzodiazol-1-yl)-3-[(2-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
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