BDBM31771 Isoconazole::cid_3760

SMILES Clc1ccc(C(Cn2ccnc2)OCc2c(Cl)cccc2Cl)c(Cl)c1

InChI Key InChIKey=MPIPASJGOJYODL-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 31771   

TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31771(Isoconazole | cid_3760)
Affinity DataIC50:  5.60E+3nMpH: 7.4 T: 37°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Swiss Institute of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM31771(Isoconazole | cid_3760)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of IDO1 (unknown origin) using L-tryptophan substrate incubated for 60 mins by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 11(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM31771(Isoconazole | cid_3760)
Affinity DataEC50: >3.50E+5nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHeme oxygenase 2(Rat)
Queen'S University

LigandPNGBDBM31771(Isoconazole | cid_3760)
Affinity DataIC50:  3.26E+4nMpH: 7.4 T: 37°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed