BDBM43662 3-phenyl-7-propan-2-yloxy-1-benzopyran-4-one::3-phenyl-7-propan-2-yloxy-chromen-4-one::3-phenyl-7-propan-2-yloxychromen-4-one::7-isopropoxy-3-phenyl-chromone::IPRIFLAVONE::MLS000069470::SMR000059060::cid_3747

SMILES CC(C)Oc1ccc2c(c1)occ(-c1ccccc1)c2=O

InChI Key InChIKey=SFBODOKJTYAUCM-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 43662   

TargetSignal transducer and activator of transcription 3 [702-738,740-752](Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43662(3-phenyl-7-propan-2-yloxy-1-benzopyran-4-one | 3-p...)
Affinity DataEC50: >5.57E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSentrin-specific protease 8(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM43662(3-phenyl-7-propan-2-yloxy-1-benzopyran-4-one | 3-p...)
Affinity DataIC50:  9.48E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Wuhan University

Curated by ChEMBL
LigandPNGBDBM43662(3-phenyl-7-propan-2-yloxy-1-benzopyran-4-one | 3-p...)
Affinity DataIC50:  2.55E+5nMAssay Description:Inhibition of MIF tautomerase (unknown origin) using 4-HPP as substrate preincubated for 1 hr followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCaspase-3(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM43662(3-phenyl-7-propan-2-yloxy-1-benzopyran-4-one | 3-p...)
Affinity DataIC50:  1.97E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSentrin-specific protease 6(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM43662(3-phenyl-7-propan-2-yloxy-1-benzopyran-4-one | 3-p...)
Affinity DataIC50:  5.72E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay