BDBM50000926 7-(2-Ethoxy-ethoxy)-1,3-dihydro-imidazo[4,5-b]quinolin-2-one(HCl)::CHEMBL91899

SMILES CCOCCOc1ccc2nc3[nH]c(=O)[nH]c3cc2c1

InChI Key InChIKey=BJHINFNFMZFKMO-UHFFFAOYSA-N

Data  1 IC50  1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50000926   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000926(7-(2-Ethoxy-ethoxy)-1,3-dihydro-imidazo[4,5-b]quin...)
Show SMILES CCOCCOc1ccc2nc3[nH]c(=O)[nH]c3cc2c1
Show InChI InChI=1S/C14H15N3O3/c1-2-19-5-6-20-10-3-4-11-9(7-10)8-12-13(15-11)17-14(18)16-12/h3-4,7-8H,2,5-6H2,1H3,(H2,15,16,17,18)
Affinity DataIC50: 50nMAssay Description:Inhibition of platelet aggregation using adenosine diphosphate (ADP) as activating agent in human platelet rich plasma (PRP)More data for this Ligand-Target Pair
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000926(7-(2-Ethoxy-ethoxy)-1,3-dihydro-imidazo[4,5-b]quin...)
Show SMILES CCOCCOc1ccc2nc3[nH]c(=O)[nH]c3cc2c1
Show InChI InChI=1S/C14H15N3O3/c1-2-19-5-6-20-10-3-4-11-9(7-10)8-12-13(15-11)17-14(18)16-12/h3-4,7-8H,2,5-6H2,1H3,(H2,15,16,17,18)
Affinity DataEC50:  4.84E+3nMAssay Description:Inhibition of platelet aggregation using Adenosine diphosphate (ADP) as activating agent in rabbit platelet rich plasma (PRP)More data for this Ligand-Target Pair