BDBM50049707 (6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxyimino]-acetylamino}-3-(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-[1,2,4]triazin-3-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid::(6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxyimino]-acetylamino}-3-(6-hydroxy-2-methyl-5-oxo-2,5-dihydro-[1,2,4]triazin-3-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid::(6R,7R,)-7-(2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-((2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-ylthio)methyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid::(6R,7R,Z)-7-(2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-((2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-ylthio)methyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid::7-[2-(2-Amino-thiazol-4-yl)-2-methoxyimino-acetylamino]-3-(6-hydroxy-2-methyl-5-oxo-2,5-dihydro-[1,2,4]triazin-3-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid (Ceftriaxone)::7-[2-(2-Amino-thiazol-4-yl)-2-methoxyimino-acetylamino]-3-(6-hydroxy-2-methyl-5-oxo-2,5-dihydro-[1,2,4]triazin-3-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid(Ceftriaxone)::CHEMBL161::ceftriaxone

SMILES: CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(CSc3nc(=O)c(=O)[nH]n3C)=C(N2C1=O)C(O)=O)c1csc(N)n1

InChI Key: InChIKey=VAAUVRVFOQPIGI-UHFFFAOYSA-N

Data: 11 KI  9 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50049707   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-binding cassette sub-family C member 4 (Human)	BDBM50049707 ((6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.56E+4	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 2 (Human)	BDBM50049707 ((6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM50049707 ((6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50049707 ((6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier family 22 member 6 (Human)	BDBM50049707 ((6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxy...) Show SMILES Show InChI	GoogleScholar	UniChem		230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier family 22 member 11 (Human)	BDBM50049707 ((6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxy...) Show SMILES Show InChI	GoogleScholar	UniChem		2.38E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier family 22 member 8 (Human)	BDBM50049707 ((6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxy...) Show SMILES Show InChI	GoogleScholar	UniChem		4.39E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM50049707 ((6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxy...) Show SMILES Show InChI	GoogleScholar	UniChem		1.58E+4	-6.55	2.10E+4	n/a	n/a	n/a	n/a	7.4	25
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Glutathione reductase, mitochondrial (Human)	BDBM50049707 ((6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxy...) Show SMILES Show InChI	GoogleScholar	UniChem		1.73E+4	n/a	2.13E+4	n/a	n/a	n/a	n/a	8.0	n/a
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Carbonic anhydrase 1 (Human)	BDBM50049707 ((6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxy...) Show SMILES Show InChI	GoogleScholar	UniChem		2.85E+4	-6.20	2.71E+4	n/a	n/a	n/a	n/a	7.4	25
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Glutathione peroxidase 1 (Human)	BDBM50049707 ((6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxy...) Show SMILES Show InChI	GoogleScholar	UniChem		3.41E+4	n/a	4.86E+4	n/a	n/a	n/a	n/a	7.0	n/a
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Microsomal glutathione S-transferase 1 (Human)	BDBM50049707 ((6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxy...) Show SMILES Show InChI	GoogleScholar	UniChem		3.54E+4	n/a	6.18E+4	n/a	n/a	n/a	n/a	6.5	n/a
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Solute carrier family 15 member 1 (Human)	BDBM50049707 ((6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxy...) Show SMILES Show InChI	GoogleScholar	UniChem		>3.00E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier family 15 member 1 (Human)	BDBM50049707 ((6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxy...) Show SMILES Show InChI	GoogleScholar	UniChem		>3.00E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier family 15 member 2 (Rat)	BDBM50049707 ((6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxy...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.00E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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