BDBM50074329 CH3-COOH::CHEMBL539::Essigsaeure::Ethylic acid::HOAc::Methanecarboxylic acid::acetic acid::acide acetique::ethoic acid

SMILES: CC(O)=O

InChI Key: InChIKey=QTBSBXVTEAMEQO-UHFFFAOYSA-N

Data: 1 IC50  3 Kd  2 EC50

PDB links: 926 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50074329   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50074329 (CH3-COOH | CHEMBL539 | Essigsaeure | Ethylic acid ...) Show SMILES CC(O)=O Show InChI InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 3 (Homo sapiens (Human))	BDBM50074329 (CH3-COOH | CHEMBL539 | Essigsaeure | Ethylic acid ...) Show SMILES CC(O)=O Show InChI InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Agonist activity at human GPCR41 transfected in HEK293 cells assessed as [35S]GTPgammaS binding by scintillation counting method				J Med Chem 61: 47-61 (2018) Article DOI: 10.1021/acs.jmedchem.7b00244 BindingDB Entry DOI: 10.7270/Q2JD507R
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Fyn (Homo sapiens (Human))	BDBM50074329 (CH3-COOH | CHEMBL539 | Essigsaeure | Ethylic acid ...) Show SMILES CC(O)=O Show InChI InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	Purchase CHEBI CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a
The Albert Einstein College of Medicine of Yeshiva University Curated by ChEMBL					Assay Description Dissociation constant for binding to SH2 domain of Fyn protein kinase				J Med Chem 42: 784-7 (1999) Article DOI: 10.1021/jm980663f BindingDB Entry DOI: 10.7270/Q2D79F4B
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50074329 (CH3-COOH | CHEMBL539 | Essigsaeure | Ethylic acid ...) Show SMILES CC(O)=O Show InChI InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a
The Albert Einstein College of Medicine of Yeshiva University Curated by ChEMBL					Assay Description Dissociation constant for binding to SH2 domain of p56 lck tyrosine kinase				J Med Chem 42: 784-7 (1999) Article DOI: 10.1021/jm980663f BindingDB Entry DOI: 10.7270/Q2D79F4B
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50074329 (CH3-COOH | CHEMBL539 | Essigsaeure | Ethylic acid ...) Show SMILES CC(O)=O Show InChI InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a
The Albert Einstein College of Medicine of Yeshiva University Curated by ChEMBL					Assay Description Dissociation constant for binding to SH2 domain of p56 lck tyrosine kinase				J Med Chem 42: 784-7 (1999) Article DOI: 10.1021/jm980663f BindingDB Entry DOI: 10.7270/Q2D79F4B
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50074329 (CH3-COOH | CHEMBL539 | Essigsaeure | Ethylic acid ...) Show SMILES CC(O)=O Show InChI InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.50E+5	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Agonist activity at human GPCR43 transfected in HEK293 cells assessed as [35S]GTPgammaS binding by scintillation counting method				J Med Chem 61: 47-61 (2018) Article DOI: 10.1021/acs.jmedchem.7b00244 BindingDB Entry DOI: 10.7270/Q2JD507R
					More data for this Ligand-Target Pair