BDBM50079022 HP2O7(3-)::diphosphate::diphosphate(3-)::hydrogen diphosphate

SMILES OP([O-])(=O)OP([O-])([O-])=O

InChI Key InChIKey=XPPKVPWEQAFLFU-UHFFFAOYSA-K

Data  5 KI  2 IC50

PDB links: 323 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50079022   

TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50079022(HP2O7(3-) | diphosphate | diphosphate(3-) | hydrog...)
Affinity DataKi:  2.98E+4nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50079022(HP2O7(3-) | diphosphate | diphosphate(3-) | hydrog...)
Affinity DataKi:  4.05E+4nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
TargetOrnithine transcarbamylase, mitochondrial(Homo sapiens (Human))
Universit£Tstrasse 16

Curated by ChEMBL
LigandPNGBDBM50079022(HP2O7(3-) | diphosphate | diphosphate(3-) | hydrog...)
Affinity DataKi:  2.40E+5nMpH: 6.0Assay Description:Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM maleate, 0.5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrnithine transcarbamylase, mitochondrial(Homo sapiens (Human))
Universit£Tstrasse 16

Curated by ChEMBL
LigandPNGBDBM50079022(HP2O7(3-) | diphosphate | diphosphate(3-) | hydrog...)
Affinity DataKi:  8.90E+5nMpH: 7.0Assay Description:Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM Tris.HCl, 0.5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrnithine transcarbamylase, mitochondrial(Homo sapiens (Human))
Universit£Tstrasse 16

Curated by ChEMBL
LigandPNGBDBM50079022(HP2O7(3-) | diphosphate | diphosphate(3-) | hydrog...)
Affinity DataKi:  2.00E+6nMpH: 8.0Assay Description:Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM Tris.HCl, 0.5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50079022(HP2O7(3-) | diphosphate | diphosphate(3-) | hydrog...)
Affinity DataIC50:  2.43E+5nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50079022(HP2O7(3-) | diphosphate | diphosphate(3-) | hydrog...)
Affinity DataIC50:  1.81E+5nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair