BDBM50232973 CHEMBL254129::CYCLOPAMINE

SMILES: C[C@H]1C[C@@H]2[C@H]([C@H]([C@]3(O2)CC[C@H]4[C@@H]5CC=C6C[C@H](CC[C@@]6([C@H]5CC4=C3C)C)O)C)NC1

InChI Key: InChIKey=QASFUMOKHFSJGL-UHFFFAOYSA-N

Data: 1 KI  11 IC50  1 Kd  1 EC50

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50232973   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sonic hedgehog protein (Mouse)	BDBM50232973 (CHEMBL254129 | CYCLOPAMINE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sonic hedgehog protein (Mouse)	BDBM50232973 (CHEMBL254129 | CYCLOPAMINE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sonic hedgehog protein (Mouse)	BDBM50232973 (CHEMBL254129 | CYCLOPAMINE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Smoothened homolog (Mouse)	BDBM50232973 (CHEMBL254129 | CYCLOPAMINE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Smoothened homolog (Human)	BDBM50232973 (CHEMBL254129 | CYCLOPAMINE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sonic hedgehog protein (Mouse)	BDBM50232973 (CHEMBL254129 | CYCLOPAMINE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Smoothened homolog (Human)	BDBM50232973 (CHEMBL254129 | CYCLOPAMINE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Smoothened homolog (Human)	BDBM50232973 (CHEMBL254129 | CYCLOPAMINE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Smoothened homolog (Mouse)	BDBM50232973 (CHEMBL254129 | CYCLOPAMINE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Smoothened homolog (Mouse)	BDBM50232973 (CHEMBL254129 | CYCLOPAMINE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sonic hedgehog protein (Human)	BDBM50232973 (CHEMBL254129 | CYCLOPAMINE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Smoothened homolog (Human)	BDBM50232973 (CHEMBL254129 | CYCLOPAMINE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	12.4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Smoothened homolog (Mouse)	BDBM50232973 (CHEMBL254129 | CYCLOPAMINE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	484	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Smoothened homolog (Human)	BDBM50232973 (CHEMBL254129 | CYCLOPAMINE) Show SMILES Show InChI	GoogleScholar	UniChem		12.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair