BDBM50263829 3-(2,4,6-Trimethoxybenzylidene)indolin-2-one::3-[(2,4,6-TRIMETHOXY-PHENYL)-METHYLENE]-INDOLIN-2-ONE::3-[(2,4,6-trimethoxyphenyl)methylidenyl]-indolin-2-one::CHEMBL489156

SMILES COc1cc(OC)c(\C=C2\C(=O)Nc3ccccc23)c(OC)c1

InChI Key InChIKey=JBJYTZXCZDNOJW-JLHYYAGUSA-N

Data  5 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50263829   

TargetCasein kinase I isoform delta(Human)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50263829(3-(2,4,6-Trimethoxybenzylidene)indolin-2-one | 3-[...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human CK1deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Human)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50263829(3-(2,4,6-Trimethoxybenzylidene)indolin-2-one | 3-[...)
Affinity DataIC50:  2.57E+3nMAssay Description:Inhibition of human CK1delta expressed in simian genome expressing mouse 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Human)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50263829(3-(2,4,6-Trimethoxybenzylidene)indolin-2-one | 3-[...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human CK1delta using casein as substrate in presence of [gamma-32P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform epsilon(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50263829(3-(2,4,6-Trimethoxybenzylidene)indolin-2-one | 3-[...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human CK1epsilon using casein as substrate in presence of [gamma-32P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50263829(3-(2,4,6-Trimethoxybenzylidene)indolin-2-one | 3-[...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of CK1 using KRRRALS(p)VASLPGL as substrate after 40 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed