BDBM50265079 (4-[1-methyl-2,4-dioxo-6-(3-phenyl-prop-1-ynyl)-1,4-dihydro-2H-quinazolin-3-ylmethyl]-benzoic acid)::4-((1-methyl-2,4-dioxo-6-(3-phenylprop-1-ynyl)-1,2-dihydroquinazolin-3(4H)-yl)methyl)benzoic acid::4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLPROP-1-YN-1-YL)-1,4-DIHYDROQUINAZOLIN-3(2H)-YL]METHYL}BENZOIC ACID::CHEMBL496942::MMP Inhibitor, 5

SMILES: CN1c2ccc(cc2C(=O)N(C1=O)Cc3ccc(cc3)C(=O)O)C#CCc4ccccc4

InChI Key: InChIKey=FLTYDFYSVZBKOB-UHFFFAOYSA-N

Data: 34 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 35 hits for monomerid = 50265079   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 2B6 (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Matrix metalloproteinase-9 (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Collagenase 3 (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.670	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Macrophage metalloelastase (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Interstitial collagenase (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrilysin (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cytochrome P450 1A2 (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cytochrome P450 2C8 (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cytochrome P450 2C19 (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cytochrome P450 2D6 (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Collagenase 3 (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Solute carrier family 22 member 8 (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neutrophil collagenase (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Collagenase 3 (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.670	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 4 (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 5 (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Stromelysin-1 (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrilysin (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Collagenase 3 (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.670	n/a	n/a	n/a	n/a	6.8	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Macrophage metalloelastase (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Collagenase 3 (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.670	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Interstitial collagenase (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Collagenase 3 (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.670	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neutrophil collagenase (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Stromelysin-1 (Human)	BDBM50265079 (CHEMBL496942 | 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLP...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair