BDBM50293925 (R)-5-Chloro-1-(1-cyclopropyl-2-methoxyethyl)-3-[2,6-dichloro-4-(trifluoromethyl)phenylamino]pyrazin-2(1H)-one::CHEMBL550216

SMILES COC[C@@H](C1CC1)n1cc(Cl)nc(Nc2c(Cl)cc(cc2Cl)C(F)(F)F)c1=O

InChI Key InChIKey=DYIVSGDVNIYLSL-LBPRGKRZSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293925   

TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50293925((R)-5-Chloro-1-(1-cyclopropyl-2-methoxyethyl)-3-[2...)
Show SMILES COC[C@@H](C1CC1)n1cc(Cl)nc(Nc2c(Cl)cc(cc2Cl)C(F)(F)F)c1=O
Show InChI InChI=1S/C17H15Cl3F3N3O2/c1-28-7-12(8-2-3-8)26-6-13(20)24-15(16(26)27)25-14-10(18)4-9(5-11(14)19)17(21,22)23/h4-6,8,12H,2-3,7H2,1H3,(H,24,25)/t12-/m0/s1
Affinity DataIC50: 1.60nMAssay Description:Displacement of [125I]ovine-CRF from CRF1 receptor in rat frontal cortex by rapid filtration techniqueMore data for this Ligand-Target Pair