BDBM50384264 CHEMBL316966

SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2CO[P@](O)(=O)O[C@H]2[C@H]1O

InChI Key InChIKey=IVOMOUWHDPKRLL-KQYNXXCUSA-N

Data  3 IC50  1 Kd

PDB links: 141 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50384264   

TargetRap guanine nucleotide exchange factor 4(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50384264(CHEMBL316966)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of EPAC2 (unknown origin)More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50384264(CHEMBL316966)
Affinity DataKd:  4.50E+3nMAssay Description:Binding affinity to GST-tagged human EPAC1 CNBD (149 to 318 residues) expressed in Escherichia coli BL21 (DE3) incubated for 30 mins by 8-NBD-cAMP ba...More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50384264(CHEMBL316966)
Affinity DataIC50:  4.80E+4nMAssay Description:Competitive inhibition of Epac2 using fluorescent nucleotide analog 8-NBD-cAMP by fluorescence analysisMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50384264(CHEMBL316966)
Affinity DataIC50:  4.00E+4nMAssay Description:Antagonist activity at recombinant EPAC2 (unknown origin) assessed 8-NBD-cAMP substrate fluorescence intensity by substrate competing assayMore data for this Ligand-Target Pair