BDBM51317 1,6-dimethylnaphtho[1,2-g][1]benzofuran-10,11-dione::1,6-dimethylnaphtho[1,2-g]benzofuran-10,11-dione::1,6-dimethylnaphtho[1,2-g]benzofuran-10,11-quinone::MLS000697676::SMR000445578::TANSHINONE I::acs.jmedchem.1c00409_ST.675::cid_114917

SMILES: Cc1coc-2c1C(=O)C(=O)c1c-2ccc2c(C)cccc12

InChI Key: InChIKey=AIGAZQPHXLWMOJ-UHFFFAOYSA-N

Data: 7 KI  16 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 51317   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Replicase polyprotein 1a (SARS-CoV)	BDBM51317 (1,6-dimethylnaphtho[1,2-g][1]benzofuran-10,11-dion...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.87E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Histone-lysine N-methyltransferase EZH2/Polycomb protein EED/Polycomb protein SUZ12 (Human)	BDBM51317 (1,6-dimethylnaphtho[1,2-g][1]benzofuran-10,11-dion...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein phosphatase non-receptor type 11 (Human)	BDBM51317 (1,6-dimethylnaphtho[1,2-g][1]benzofuran-10,11-dion...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein phosphatase non-receptor type 6 (Human)	BDBM51317 (1,6-dimethylnaphtho[1,2-g][1]benzofuran-10,11-dion...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.97E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Replicase polyprotein 1a (SARS-CoV)	BDBM51317 (1,6-dimethylnaphtho[1,2-g][1]benzofuran-10,11-dion...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
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Replicase polyprotein 1a (SARS-CoV)	BDBM51317 (1,6-dimethylnaphtho[1,2-g][1]benzofuran-10,11-dion...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Replicase polyprotein 1a (SARS-CoV)	BDBM51317 (1,6-dimethylnaphtho[1,2-g][1]benzofuran-10,11-dion...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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DNA repair protein RAD51 homolog 1 (Human)	BDBM51317 (1,6-dimethylnaphtho[1,2-g][1]benzofuran-10,11-dion...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (2019-nCoV)	BDBM51317 (1,6-dimethylnaphtho[1,2-g][1]benzofuran-10,11-dion...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific histone demethylase 1A (Human)	BDBM51317 (1,6-dimethylnaphtho[1,2-g][1]benzofuran-10,11-dion...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific histone demethylase 1A (Human)	BDBM51317 (1,6-dimethylnaphtho[1,2-g][1]benzofuran-10,11-dion...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Human)	BDBM51317 (1,6-dimethylnaphtho[1,2-g][1]benzofuran-10,11-dion...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aldo-keto reductase family 1 member B1 (Rat)	BDBM51317 (1,6-dimethylnaphtho[1,2-g][1]benzofuran-10,11-dion...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Endothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha (Human)	BDBM51317 (1,6-dimethylnaphtho[1,2-g][1]benzofuran-10,11-dion...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Endothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha (Human)	BDBM51317 (1,6-dimethylnaphtho[1,2-g][1]benzofuran-10,11-dion...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (SARS-CoV)	BDBM51317 (1,6-dimethylnaphtho[1,2-g][1]benzofuran-10,11-dion...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.87E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Streptokinase A (Streptococcus pyogenes M1 GAS)	BDBM51317 (1,6-dimethylnaphtho[1,2-g][1]benzofuran-10,11-dion...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a
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Cocaine esterase (Human)	BDBM51317 (1,6-dimethylnaphtho[1,2-g][1]benzofuran-10,11-dion...) Show SMILES Show InChI	GoogleScholar	UniChem		1.41E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Replicase polyprotein 1a (SARS-CoV)	BDBM51317 (1,6-dimethylnaphtho[1,2-g][1]benzofuran-10,11-dion...) Show SMILES Show InChI	GoogleScholar	UniChem		1.37E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (SARS-CoV)	BDBM51317 (1,6-dimethylnaphtho[1,2-g][1]benzofuran-10,11-dion...) Show SMILES Show InChI	GoogleScholar	UniChem		1.37E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cocaine esterase (Human)	BDBM51317 (1,6-dimethylnaphtho[1,2-g][1]benzofuran-10,11-dion...) Show SMILES Show InChI	GoogleScholar	UniChem		1.46E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Liver carboxylesterase 1 (Human)	BDBM51317 (1,6-dimethylnaphtho[1,2-g][1]benzofuran-10,11-dion...) Show SMILES Show InChI	GoogleScholar	UniChem		2.63E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM51317 (1,6-dimethylnaphtho[1,2-g][1]benzofuran-10,11-dion...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM51317 (1,6-dimethylnaphtho[1,2-g][1]benzofuran-10,11-dion...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair