BDBM5566 2,6-Diamino-4-cyclohexylmethoxy-5-nitrosopyrimidine::6-(cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diamine::NU6027::pyrimidine deriv.
SMILES Nc1nc(N)c(N=O)c(OCC2CCCCC2)n1
InChI Key InChIKey=DGWXOLHKVGDQLN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 5566
Affinity DataKi: 1.30E+3nM ΔG°: -8.16kcal/molepH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Instituto Universitario De Bio-Org£Nica Antonio Gonz£Lez (Iubo-Ag)
Curated by ChEMBL
Instituto Universitario De Bio-Org£Nica Antonio Gonz£Lez (Iubo-Ag)
Curated by ChEMBL
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Instituto Universitario De Bio-Org£Nica Antonio Gonz£Lez (Iubo-Ag)
Curated by ChEMBL
Instituto Universitario De Bio-Org£Nica Antonio Gonz£Lez (Iubo-Ag)
Curated by ChEMBL
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
University Of Newcastle
University Of Newcastle
Affinity DataKi: 2.50E+3nM ΔG°: -7.77kcal/molepH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of flag-tagged ATR expressed in HEK293T cells using PHAS-1 as substrate after 20 mins by autoradiographyMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of CDK1/Cyclin B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of CDK2/cyclinA (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
University Of South Australia Cancer Research Institute
Curated by ChEMBL
University Of South Australia Cancer Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human CDK2/Cyclin A expressed in baculovirus infected Sf9 insect cellsMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
University Of Newcastle
University Of Newcastle
Affinity DataIC50: 2.90E+3nMpH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMpH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
University Of Newcastle
University Of Newcastle
Affinity DataIC50: 2.90E+3nMpH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMpH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair