BDBM81395 APO-866::US20240300968, Example Comparative FK8661::US20240327418, Example FK866

SMILES: c1ccc(cc1)C(=O)N2CCC(CC2)CCCCNC(=O)/C=C/c3cccnc3

InChI Key: InChIKey=KPBNHDGDUADAGP-UHFFFAOYSA-N

Data: 2 KI  30 IC50  1 Kd

PDB links: 4 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 41 hits for monomerid = 81395   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 2 (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.48E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mouse)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	96.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Mouse)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.560	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Human)	BDBM81395 (APO-866 | US20240327418, Example FK866 | US2024030...) Show SMILES Show InChI	GoogleScholar	UniChem		3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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