BDBM18134 ({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}amino)phosphonic acid::5-Adenylyl imidodiphosphate::AMP.P[NH]P::AMPPNP

SMILES: c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@](=O)(O)O[P@@](=O)(NP(=O)(O)O)O)O)O)N

InChI Key: InChIKey=PVKSNHVPLWYQGJ-UHFFFAOYSA-N

Data: 4 KI  2 IC50  10 ITC

PDB links: 1177 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 18134   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sensor protein kinase WalK (Staphylococcus aureus)	BDBM18134 (AMP.P[NH]P | 5-Adenylyl imidodiphosphate | ({[({[(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-1/type-2 (Rat)	BDBM18134 (AMP.P[NH]P | 5-Adenylyl imidodiphosphate | ({[({[(...) Show SMILES Show InChI	GoogleScholar	UniChem		4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Rat)	BDBM18134 (AMP.P[NH]P | 5-Adenylyl imidodiphosphate | ({[({[(...) Show SMILES Show InChI	GoogleScholar	UniChem		5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycine--tRNA ligase (Silk moth)	BDBM18134 (AMP.P[NH]P | 5-Adenylyl imidodiphosphate | ({[({[(...) Show SMILES Show InChI	GoogleScholar	UniChem		2.00E+4	-6.41	1.00E+5	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycerol kinase (Human)	BDBM18134 (AMP.P[NH]P | 5-Adenylyl imidodiphosphate | ({[({[(...) Show SMILES Show InChI	GoogleScholar	UniChem		9.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair

Activity Spreadsheet -- ITC Data from BindingDB

Found 10 hits for monomerid = 18134

Cell (A)	Syringe (B)	Cell Links	Syringe Links	Cell + Syr Links	ΔG° kcal/mole	-TΔS° kcal/mole	ΔH° kcal/mole	log K	pH	Temp °C
tRNA synthetase (GlyRS) (Silk moth)	BDBM18134 (AMP.P[NH]P | 5-Adenylyl imidodiphosphate | ({[({[(...)	GoogleScholar			-7.57	9.29	-16.2	5.57	7.20	24.9
TBA					Details of this binding reaction
Heat Shock Protein 90 (Hsp90) (Baker's yeast)	BDBM18134 (AMP.P[NH]P | 5-Adenylyl imidodiphosphate | ({[({[(...)	GoogleScholar			-5.61	3.56	-9.17	4.36	8	8
TBA					Details of this binding reaction
Heat Shock Protein 90 (Hsp90) (Baker's yeast)	BDBM18134 (AMP.P[NH]P | 5-Adenylyl imidodiphosphate | ({[({[(...)	GoogleScholar			-5.57	3.10	-8.67	4.28	8	10
TBA					Details of this binding reaction
Heat Shock Protein 90 (Hsp90) (Baker's yeast)	BDBM18134 (AMP.P[NH]P | 5-Adenylyl imidodiphosphate | ({[({[(...)	GoogleScholar			-5.45	3.13	-8.57	4.11	8	15
TBA					Details of this binding reaction
Heat Shock Protein 90 (Hsp90) (Baker's yeast)	BDBM18134 (AMP.P[NH]P | 5-Adenylyl imidodiphosphate | ({[({[(...)	GoogleScholar			-5.40	2.77	-8.17	4.04	8	20
TBA					Details of this binding reaction
Heat Shock Protein 90 (Hsp90) (Baker's yeast)	BDBM18134 (AMP.P[NH]P | 5-Adenylyl imidodiphosphate | ({[({[(...)	GoogleScholar			-5.30	2.68	-7.98	3.89	8	25
TBA					Details of this binding reaction
Heat Shock Protein 90 (Hsp90) (Baker's yeast)	BDBM18134 (AMP.P[NH]P | 5-Adenylyl imidodiphosphate | ({[({[(...)	GoogleScholar			-5.59	3.42	-9.02	4.34	8	8
TBA					Details of this binding reaction
Heat Shock Protein 90 (Hsp90) (Baker's yeast)	BDBM18134 (AMP.P[NH]P | 5-Adenylyl imidodiphosphate | ({[({[(...)	GoogleScholar			-5.56	2.97	-8.52	4.26	8	12
TBA					Details of this binding reaction
Heat Shock Protein 90 (Hsp90) (Baker's yeast)	BDBM18134 (AMP.P[NH]P | 5-Adenylyl imidodiphosphate | ({[({[(...)	GoogleScholar			-5.47	2.72	-8.20	4.15	8	16
TBA					Details of this binding reaction
Heat Shock Protein 90 (Hsp90) (Baker's yeast)	BDBM18134 (AMP.P[NH]P | 5-Adenylyl imidodiphosphate | ({[({[(...)	GoogleScholar			-5.48	2.33	-7.81	3.93	8	25
TBA					Details of this binding reaction