BDBM8037 2-Anilino-4-(thiazol-5-yl)pyrimidine deriv. 8::4-(2,4-Dimethylthiazol-5-yl)pyrimidin-2-ylamine::4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine::4-(dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine, 1::CS12

SMILES: Cc1nc(C)c(s1)-c1ccnc(N)n1

InChI Key: InChIKey=CTFDMGIBHFQWKB-UHFFFAOYSA-N

Data: 4 KI  3 IC50  2 Kd  1 K_off  1 K_on

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 8037   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2 (Human)	BDBM8037 (4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-A2/Cyclin-dependent kinase 2 (Human)	BDBM8037 (4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-A2/Cyclin-dependent kinase 2 (Human)	BDBM8037 (4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.03E+4	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Human)	BDBM8037 (4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.03E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Human)	BDBM8037 (4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	8.22E+4	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Human)	BDBM8037 (4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	1.42	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM8037 (4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Human)	BDBM8037 (4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine...) Show SMILES Show InChI	GoogleScholar	UniChem		396	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM8037 (4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine...) Show SMILES Show InChI	GoogleScholar	UniChem		6.50E+3	-7.19	n/a	n/a	n/a	n/a	n/a	7.4	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM8037 (4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine...) Show SMILES Show InChI	GoogleScholar	UniChem		6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Human)	BDBM8037 (4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine...) Show SMILES Show InChI	GoogleScholar	UniChem		1.60E+4	-6.65	n/a	n/a	n/a	n/a	n/a	n/a	30
TBA									Citation and Details
					More data for this Ligand-Target Pair