BDBM8068 2-Anilino-4-(thiazol-5-yl)pyrimidine deriv. 39::2-Chloro-N4-[4-(2,4-dimethylthiazol-5-yl)pyrimidin-2-yl]-N1,N1-dimethylbenzene-1,4-diamine::2-chloro-4-N-[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-1-N,1-N-dimethylbenzene-1,4-diamine::CS20

SMILES: CN(C)c1ccc(Nc2nccc(n2)-c2sc(C)nc2C)cc1Cl

InChI Key: InChIKey=FUDBRAFSKPGJJE-UHFFFAOYSA-N

Data: 2 KI  5 Kd  2 K_off  2 K_on

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 8068   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2 (Human)	BDBM8068 (2-chloro-4-N-[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.97E+4	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Human)	BDBM8068 (2-chloro-4-N-[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	777	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-A2/Cyclin-dependent kinase 2 (Human)	BDBM8068 (2-chloro-4-N-[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	45	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Human)	BDBM8068 (2-chloro-4-N-[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	44.8	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Human)	BDBM8068 (2-chloro-4-N-[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	6.02E+5	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Human)	BDBM8068 (2-chloro-4-N-[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0170	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Human)	BDBM8068 (2-chloro-4-N-[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	777	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Human)	BDBM8068 (2-chloro-4-N-[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	8.59E+4	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Human)	BDBM8068 (2-chloro-4-N-[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.0562	n/a	n/a	n/a
TBA									Citation and Details
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Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM8068 (2-chloro-4-N-[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		100	-9.70	n/a	n/a	n/a	n/a	n/a	n/a	30
TBA									Citation and Details
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Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Human)	BDBM8068 (2-chloro-4-N-[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		1.00E+3	-8.32	n/a	n/a	n/a	n/a	n/a	n/a	30
TBA									Citation and Details
					More data for this Ligand-Target Pair