BDBM10278 3-Chloro-N-(1,2,3,4-tetrahydro-1,3,4-trioxoisoquinolin-6-yl)-propanamide::3-chloro-N-(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-6-yl)propanamide::Isoquinoline-1,3,4-trione 9k

SMILES: ClCCC(=O)Nc1ccc2C(=O)NC(=O)C(=O)c2c1

InChI Key: InChIKey=XNELIBGPKZNEOG-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 10278   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Caspase-3 (Human)	BDBM10278 (3-Chloro-N-(1,2,3,4-tetrahydro-1,3,4-trioxoisoquin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
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Caspase-2 (Human)	BDBM10278 (3-Chloro-N-(1,2,3,4-tetrahydro-1,3,4-trioxoisoquin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Caspase-6 (Human)	BDBM10278 (3-Chloro-N-(1,2,3,4-tetrahydro-1,3,4-trioxoisoquin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	283	n/a	n/a	n/a	n/a	n/a	n/a
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Caspase-7 (Human)	BDBM10278 (3-Chloro-N-(1,2,3,4-tetrahydro-1,3,4-trioxoisoquin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	139	n/a	n/a	n/a	n/a	n/a	n/a
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Caspase-8 (Human)	BDBM10278 (3-Chloro-N-(1,2,3,4-tetrahydro-1,3,4-trioxoisoquin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	575	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair