BDBM10287 Isoquinoline-1,3,4-trione 13f::N-(2-Methoxy-phenyl)-N-(1,3,4-trioxo-1,2,3,4-tetrahydro-isoquinolin-6-yl)-succinamide::N-(2-methoxyphenyl)-N'-(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-6-yl)butanediamide

SMILES: COc1ccccc1NC(=O)CCC(=O)Nc1ccc2C(=O)NC(=O)C(=O)c2c1

InChI Key: InChIKey=CXBBLGYLOAZXJT-UHFFFAOYSA-N

Data: 5 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 10287   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Caspase-3 (Human)	BDBM10287 (N-(2-Methoxy-phenyl)-N-(1,3,4-trioxo-1,2,3,4-tetra...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	113	n/a	n/a	n/a	n/a	n/a	n/a
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Caspase-2 (Human)	BDBM10287 (N-(2-Methoxy-phenyl)-N-(1,3,4-trioxo-1,2,3,4-tetra...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	537	n/a	n/a	n/a	n/a	n/a	n/a
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Caspase-6 (Human)	BDBM10287 (N-(2-Methoxy-phenyl)-N-(1,3,4-trioxo-1,2,3,4-tetra...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	137	n/a	n/a	n/a	n/a	n/a	n/a
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Caspase-7 (Human)	BDBM10287 (N-(2-Methoxy-phenyl)-N-(1,3,4-trioxo-1,2,3,4-tetra...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	218	n/a	n/a	n/a	n/a	n/a	n/a
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Caspase-8 (Human)	BDBM10287 (N-(2-Methoxy-phenyl)-N-(1,3,4-trioxo-1,2,3,4-tetra...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	835	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair