BDBM10323 (S)-1-Benzyl-5-{1-[2-(phenoxymethyl)pyrrolidinyl]sulfonyl}isatin::1-benzyl-5-{[(2S)-2-(phenoxymethyl)pyrrolidine-1-]sulfonyl}-2,3-dihydro-1H-indole-2,3-dione::CHEMBL439753::IST-3::Isatin Sulfonamide 34::JMC522188 Compound 2::Pyrrolidine Isatin Analogue 2

SMILES: O=C1N(Cc2ccccc2)c2ccc(cc2C1=O)S(=O)(=O)N1CCC[C@H]1COc1ccccc1

InChI Key: InChIKey=PKOUAUWPBMZQCH-UHFFFAOYSA-N

Data: 9 KI  9 IC50  6 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 10323   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Caspase-6 (Human)	BDBM10323 (JMC522188 Compound 2 | IST-3 | CHEMBL439753 | 1-be...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Caspase-3 (Human)	BDBM10323 (JMC522188 Compound 2 | IST-3 | CHEMBL439753 | 1-be...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12.3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Caspase-3 (Human)	BDBM10323 (JMC522188 Compound 2 | IST-3 | CHEMBL439753 | 1-be...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.67E+3	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Caspase-3 (Human)	BDBM10323 (JMC522188 Compound 2 | IST-3 | CHEMBL439753 | 1-be...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	41.8	n/a	n/a	n/a	n/a
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Caspase-8 (Human)	BDBM10323 (JMC522188 Compound 2 | IST-3 | CHEMBL439753 | 1-be...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Caspase-6 (Human)	BDBM10323 (JMC522188 Compound 2 | IST-3 | CHEMBL439753 | 1-be...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Caspase-1 (Human)	BDBM10323 (JMC522188 Compound 2 | IST-3 | CHEMBL439753 | 1-be...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Caspase-7 (Human)	BDBM10323 (JMC522188 Compound 2 | IST-3 | CHEMBL439753 | 1-be...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	29.4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Caspase-3 (Human)	BDBM10323 (JMC522188 Compound 2 | IST-3 | CHEMBL439753 | 1-be...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Caspase-6 (Human)	BDBM10323 (JMC522188 Compound 2 | IST-3 | CHEMBL439753 | 1-be...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Caspase-8 (Human)	BDBM10323 (JMC522188 Compound 2 | IST-3 | CHEMBL439753 | 1-be...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Caspase-1 (Human)	BDBM10323 (JMC522188 Compound 2 | IST-3 | CHEMBL439753 | 1-be...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Caspase-7 (Human)	BDBM10323 (JMC522188 Compound 2 | IST-3 | CHEMBL439753 | 1-be...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Caspase-3 (Human)	BDBM10323 (JMC522188 Compound 2 | IST-3 | CHEMBL439753 | 1-be...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12.2	n/a	n/a	n/a	n/a	7.4	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Caspase-3 (Human)	BDBM10323 (JMC522188 Compound 2 | IST-3 | CHEMBL439753 | 1-be...) Show SMILES Show InChI	GoogleScholar	UniChem		1.20	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Caspase-3 (Human)	BDBM10323 (JMC522188 Compound 2 | IST-3 | CHEMBL439753 | 1-be...) Show SMILES Show InChI	GoogleScholar	UniChem		2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Caspase-7 (Human)	BDBM10323 (JMC522188 Compound 2 | IST-3 | CHEMBL439753 | 1-be...) Show SMILES Show InChI	GoogleScholar	UniChem		6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Caspase-9 (Human)	BDBM10323 (JMC522188 Compound 2 | IST-3 | CHEMBL439753 | 1-be...) Show SMILES Show InChI	GoogleScholar	UniChem		120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Caspase-2 (Human)	BDBM10323 (JMC522188 Compound 2 | IST-3 | CHEMBL439753 | 1-be...) Show SMILES Show InChI	GoogleScholar	UniChem		4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Caspase-8 (Human)	BDBM10323 (JMC522188 Compound 2 | IST-3 | CHEMBL439753 | 1-be...) Show SMILES Show InChI	GoogleScholar	UniChem		>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Caspase-6 (Human)	BDBM10323 (JMC522188 Compound 2 | IST-3 | CHEMBL439753 | 1-be...) Show SMILES Show InChI	GoogleScholar	UniChem		>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Caspase-4 (Human)	BDBM10323 (JMC522188 Compound 2 | IST-3 | CHEMBL439753 | 1-be...) Show SMILES Show InChI	GoogleScholar	UniChem		>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Caspase-1 (Human)	BDBM10323 (JMC522188 Compound 2 | IST-3 | CHEMBL439753 | 1-be...) Show SMILES Show InChI	GoogleScholar	UniChem		>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair