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BDBM107237 US8598345, Table 1-23

SMILES: O=C(Nc1ccncn1)c1cc(Oc2cccnc2)ccn1

InChI Key: InChIKey=AODJWRXPLVIUQR-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 107237   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor


(Rattus norvegicus (Rat))
BDBM107237
PNG
(US8598345, Table 1-23)
Show SMILES O=C(Nc1ccncn1)c1cc(Oc2cccnc2)ccn1
Show InChI InChI=1S/C15H11N5O2/c21-15(20-14-4-6-17-10-19-14)13-8-11(3-7-18-13)22-12-2-1-5-16-9-12/h1-10H,(H,17,19,20,21)
PDB
MMDB

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PC cid
PC sid
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Similars

US Patent
n/an/a 4.69E+3n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
mGluR5 activity was determined in a cell-based assay.


US Patent US8598345 (2013)


BindingDB Entry DOI: 10.7270/Q2RR1WX8
More data for this
Ligand-Target Pair