BDBM112498 US8623883, No. 1

SMILES FCCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN1CCCCC1

InChI Key InChIKey=GFMMDHSSOIPFTF-SNAWJCMRSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 112498   

TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Warner-Lambert

US Patent
LigandPNGBDBM112498(US8623883, No. 1)
Affinity DataIC50:  77.5nMpH: 7.4 T: 2°CAssay Description:Inhibition of erbB tyrosine kinase activity was assessed using an ELISA-based receptor tyrosine kinase assay. Kinase reactions (50 mM HEPES, pH 7.4, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Warner-Lambert

US Patent
LigandPNGBDBM112498(US8623883, No. 1)
Affinity DataIC50:  6.44nMpH: 7.4 T: 2°CAssay Description:Inhibition of erbB tyrosine kinase activity was assessed using an ELISA-based receptor tyrosine kinase assay. Kinase reactions (50 mM HEPES, pH 7.4, ...More data for this Ligand-Target Pair
In DepthDetails US Patent