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BDBM120008 US8697869, 1

SMILES: OC(=O)Cn1c2CC[C@@H](Cc2c2cc(F)ccc12)Nc1ncc(F)cn1

InChI Key: InChIKey=ABVWNFNHZIHFOG-LBPRGKRZSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120008   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM120008
PNG
(US8697869, 1)
Show SMILES OC(=O)Cn1c2CC[C@@H](Cc2c2cc(F)ccc12)Nc1ncc(F)cn1
Show InChI InChI=1S/C18H16F2N4O2/c19-10-1-3-15-13(5-10)14-6-12(23-18-21-7-11(20)8-22-18)2-4-16(14)24(15)9-17(25)26/h1,3,5,7-8,12H,2,4,6,9H2,(H,25,26)(H,21,22,23)/t12-/m0/s1
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Similars

US Patent
n/an/a 16n/an/an/an/a7.0n/a



Actelion Pharmaceuticals Ltd.

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 μl. First, 25 μl of test compound, previously diluted in Binding-Buffer (Binding...


US Patent US8697869 (2014)


BindingDB Entry DOI: 10.7270/Q2251GVB
More data for this
Ligand-Target Pair