BDBM12355 3-(thiophen-3-yl)pyridine::CHEMBL361153::US8609708,11::nicotine 3-heteroaromatic analogue 8

SMILES: c1cc(cs1)-c1cccnc1

InChI Key: InChIKey=FQCXYANVLWAPNK-UHFFFAOYSA-N

Data: 3 KI  9 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 12355   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 2A6 (Human)	BDBM12355 (3-(thiophen-3-yl)pyridine | US8609708,11 | CHEMBL3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.37E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM12355 (3-(thiophen-3-yl)pyridine | US8609708,11 | CHEMBL3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2A6 (Human)	BDBM12355 (3-(thiophen-3-yl)pyridine | US8609708,11 | CHEMBL3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM12355 (3-(thiophen-3-yl)pyridine | US8609708,11 | CHEMBL3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.69E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2E1 (Human)	BDBM12355 (3-(thiophen-3-yl)pyridine | US8609708,11 | CHEMBL3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM12355 (3-(thiophen-3-yl)pyridine | US8609708,11 | CHEMBL3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM12355 (3-(thiophen-3-yl)pyridine | US8609708,11 | CHEMBL3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM12355 (3-(thiophen-3-yl)pyridine | US8609708,11 | CHEMBL3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.48E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2B6 (Human)	BDBM12355 (3-(thiophen-3-yl)pyridine | US8609708,11 | CHEMBL3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.91E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2A6 (Human)	BDBM12355 (3-(thiophen-3-yl)pyridine | US8609708,11 | CHEMBL3...) Show SMILES Show InChI	GoogleScholar	UniChem		220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2A6 (Human)	BDBM12355 (3-(thiophen-3-yl)pyridine | US8609708,11 | CHEMBL3...) Show SMILES Show InChI	GoogleScholar	UniChem		700	-8.73	n/a	n/a	n/a	n/a	n/a	7.5	37
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Cytochrome P450 3A4 (Human)	BDBM12355 (3-(thiophen-3-yl)pyridine | US8609708,11 | CHEMBL3...) Show SMILES Show InChI	GoogleScholar	UniChem		2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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