BDBM12357 3-(1H-imidazol-4-yl)pyridine::CHEMBL178516::JMC514968 Compound 7::US8609708, 14::US8609708,14::nicotine 3-heteroaromatic analogue 10

SMILES: c1nc(c[nH]1)-c1cccnc1

InChI Key: InChIKey=YFOKBFRTGLSZLU-UHFFFAOYSA-N

Data: 3 KI  12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 12357   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM12357 (CHEMBL178516 | US8609708, 14 | 3-(1H-imidazol-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2A6 (Human)	BDBM12357 (CHEMBL178516 | US8609708, 14 | 3-(1H-imidazol-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2A6 (Human)	BDBM12357 (CHEMBL178516 | US8609708, 14 | 3-(1H-imidazol-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM12357 (CHEMBL178516 | US8609708, 14 | 3-(1H-imidazol-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2A6 (Human)	BDBM12357 (CHEMBL178516 | US8609708, 14 | 3-(1H-imidazol-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.00E+5	n/a	n/a	n/a	n/a	7.5	n/a
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Cytochrome P450 2B6 (Human)	BDBM12357 (CHEMBL178516 | US8609708, 14 | 3-(1H-imidazol-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.03E+5	n/a	n/a	n/a	n/a	7.5	n/a
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					More data for this Ligand-Target Pair
Cytochrome P450 2A6 (Human)	BDBM12357 (CHEMBL178516 | US8609708, 14 | 3-(1H-imidazol-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cytochrome P450 2B6 (Human)	BDBM12357 (CHEMBL178516 | US8609708, 14 | 3-(1H-imidazol-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.03E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM12357 (CHEMBL178516 | US8609708, 14 | 3-(1H-imidazol-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM12357 (CHEMBL178516 | US8609708, 14 | 3-(1H-imidazol-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM12357 (CHEMBL178516 | US8609708, 14 | 3-(1H-imidazol-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM12357 (CHEMBL178516 | US8609708, 14 | 3-(1H-imidazol-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2E1 (Human)	BDBM12357 (CHEMBL178516 | US8609708, 14 | 3-(1H-imidazol-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2A6 (Human)	BDBM12357 (CHEMBL178516 | US8609708, 14 | 3-(1H-imidazol-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2A6 (Human)	BDBM12357 (CHEMBL178516 | US8609708, 14 | 3-(1H-imidazol-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM12357 (CHEMBL178516 | US8609708, 14 | 3-(1H-imidazol-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		7.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair