BDBM14058 CHEMBL316053::N-[(3S)-1-[(1-aminoisoquinolin-7-yl)methyl]-2-oxo-pyrrolidin-3-yl]-7-thia-2-azabicyclo[4.3.0]nona-2,4,8,10-tetraene-8-sulfonamide::N-[(3S)-1-[(1-aminoisoquinolin-7-yl)methyl]-2-oxopyrrolidin-3-yl]thieno[3,2-b]pyridine-2-sulfonamide::RPR208815

SMILES: Nc1nccc2ccc(CN3CC[C@H](NS(=O)(=O)c4cc5ncccc5s4)C3=O)cc12

InChI Key: InChIKey=NVKDOURNRJCKJE-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 14058   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Human)	BDBM14058 (N-[(3S)-1-[(1-aminoisoquinolin-7-yl)methyl]-2-oxop...) Show SMILES Show InChI	GoogleScholar	UniChem		22	-10.3	n/a	n/a	n/a	n/a	n/a	7.5	22
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Coagulation factor X (Bovine)	BDBM14058 (N-[(3S)-1-[(1-aminoisoquinolin-7-yl)methyl]-2-oxop...) Show SMILES Show InChI	GoogleScholar	UniChem		22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Coagulation factor X (Human)	BDBM14058 (N-[(3S)-1-[(1-aminoisoquinolin-7-yl)methyl]-2-oxop...) Show SMILES Show InChI	GoogleScholar	UniChem		22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Serine protease 1 (Bovine)	BDBM14058 (N-[(3S)-1-[(1-aminoisoquinolin-7-yl)methyl]-2-oxop...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.90E+3	>-7.47	n/a	n/a	n/a	n/a	n/a	7.5	22
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Prothrombin (Human)	BDBM14058 (N-[(3S)-1-[(1-aminoisoquinolin-7-yl)methyl]-2-oxop...) Show SMILES Show InChI	GoogleScholar	UniChem		>4.00E+3	>-7.28	n/a	n/a	n/a	n/a	n/a	7.5	22
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					More data for this Ligand-Target Pair