BDBM143797 US10183953, Example 58::US8969352, 58::US9611277, Example 58::US9845333, 58

SMILES: Fc1ccc(-c2ncccn2)c(c1)C(=O)N1CC2CC(Nc3ccc(cn3)C(F)(F)F)C1C2

InChI Key: InChIKey=CKIBODIXGNACEX-UHFFFAOYSA-N

Data: 18 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 143797   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin/Hypocretin receptor type 1 (Human)	BDBM143797 (US8969352, 58 | US9611277, Example 58 | US10183953...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Human)	BDBM143797 (US8969352, 58 | US9611277, Example 58 | US10183953...) Show SMILES Show InChI	GoogleScholar	UniChem		2	-11.0	n/a	n/a	n/a	n/a	n/a	n/a	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Human)	BDBM143797 (US8969352, 58 | US9611277, Example 58 | US10183953...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Human)	BDBM143797 (US8969352, 58 | US9611277, Example 58 | US10183953...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Human)	BDBM143797 (US8969352, 58 | US9611277, Example 58 | US10183953...) Show SMILES Show InChI	GoogleScholar	UniChem		3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Human)	BDBM143797 (US8969352, 58 | US9611277, Example 58 | US10183953...) Show SMILES Show InChI	GoogleScholar	UniChem		3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rat)	BDBM143797 (US8969352, 58 | US9611277, Example 58 | US10183953...) Show SMILES Show InChI	GoogleScholar	UniChem		4	-10.6	n/a	n/a	n/a	n/a	n/a	n/a	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rat)	BDBM143797 (US8969352, 58 | US9611277, Example 58 | US10183953...) Show SMILES Show InChI	GoogleScholar	UniChem		4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rat)	BDBM143797 (US8969352, 58 | US9611277, Example 58 | US10183953...) Show SMILES Show InChI	GoogleScholar	UniChem		4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rat)	BDBM143797 (US8969352, 58 | US9611277, Example 58 | US10183953...) Show SMILES Show InChI	GoogleScholar	UniChem		4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rat)	BDBM143797 (US8969352, 58 | US9611277, Example 58 | US10183953...) Show SMILES Show InChI	GoogleScholar	UniChem		5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rat)	BDBM143797 (US8969352, 58 | US9611277, Example 58 | US10183953...) Show SMILES Show InChI	GoogleScholar	UniChem		5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Human)	BDBM143797 (US8969352, 58 | US9611277, Example 58 | US10183953...) Show SMILES Show InChI	GoogleScholar	UniChem		181	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Rat)	BDBM143797 (US8969352, 58 | US9611277, Example 58 | US10183953...) Show SMILES Show InChI	GoogleScholar	UniChem		181	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Human)	BDBM143797 (US8969352, 58 | US9611277, Example 58 | US10183953...) Show SMILES Show InChI	GoogleScholar	UniChem		181	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Human)	BDBM143797 (US8969352, 58 | US9611277, Example 58 | US10183953...) Show SMILES Show InChI	GoogleScholar	UniChem		181	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Human)	BDBM143797 (US8969352, 58 | US9611277, Example 58 | US10183953...) Show SMILES Show InChI	GoogleScholar	UniChem		193	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Human)	BDBM143797 (US8969352, 58 | US9611277, Example 58 | US10183953...) Show SMILES Show InChI	GoogleScholar	UniChem		193	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair