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BDBM14397 5-(5-acetyl-2-ethoxyphenyl)-1-methyl-3-propyl-1H,6H,7H-pyrazolo[4,3-d]pyrimidin-7-one::Sildenafil 5-methyl ketone analogue 57

SMILES: CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)C(C)=O

InChI Key: InChIKey=YJBDHZKAVGNHET-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14397   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cGMP-specific 3',5'-cyclic phosphodiesterase


(Human)
BDBM14397
PNG
(5-(5-acetyl-2-ethoxyphenyl)-1-methyl-3-propyl-1H,6...)
GoogleScholar
UniChem
n/an/a 17n/an/an/an/a7.430


TBA



Citation and Details
More data for this
Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma


(Dog)
BDBM14397
PNG
(5-(5-acetyl-2-ethoxyphenyl)-1-methyl-3-propyl-1H,6...)
GoogleScholar
UniChem
n/an/a 0.900n/an/an/an/a7.430


TBA



Citation and Details
More data for this
Ligand-Target Pair