BDBM14704 1,3-diethyl 2-{[(2-methylphenyl)amino]methylidene}propanedioate::2-(o-Tolylamino-methylene)-malonic acid diethyl ester::monocyclic compound 9
SMILES CCOC(=O)C(C=Nc1ccccc1C)C(=O)OCC
InChI Key InChIKey=DKJGJYLQPURRFB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 14704
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Leeds
University of Leeds
Affinity DataKi: 3.59E+4nM IC50: 2.92E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Leeds
University of Leeds
Affinity DataKi: 3.97E+4nM ΔG°: -6.00kcal/mole IC50: 3.46E+5nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair