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BDBM150906 US8981106, 95

SMILES: Fc1ccc(NC(=O)c2ccc(SCC(=O)c3ccc(F)c(F)c3)nc2)cc1

InChI Key: InChIKey=ATMVQEHTDOIWFZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 150906   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-X-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM150906
PNG
(US8981106, 95)
Show SMILES Fc1ccc(NC(=O)c2ccc(SCC(=O)c3ccc(F)c(F)c3)nc2)cc1
Show InChI InChI=1S/C20H13F3N2O2S/c21-14-3-5-15(6-4-14)25-20(27)13-2-8-19(24-10-13)28-11-18(26)12-1-7-16(22)17(23)9-12/h1-10H,11H2,(H,25,27)
PDB

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PC cid
PC sid
UniChem

Similars

US Patent
n/an/a>5.00E+3n/an/an/an/an/a37



Syntrix Biosystems, Inc.

US Patent


Assay Description
An in vitro assay showed inhibition of CXCR2-mediated intracellular calcium release. Briefly, human neutrophils were suspended in HBSS- (without Ca2+...


US Patent US8981106 (2015)


BindingDB Entry DOI: 10.7270/Q2WW7GC1
More data for this
Ligand-Target Pair