BDBM164066 US9062078, 196::US9475819, 196::US9637496, 196::US9695183, 196

SMILES: FC(F)(F)c1ccc(NC2CC3CCC2N3C(=O)c2ccccc2-n2nccn2)nc1

InChI Key:

Data: 14 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 164066   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin/Hypocretin receptor type 1 (Human)	BDBM164066 (US9475819, 196 | US9062078, 196 | US9695183, 196 |...) Show SMILES Show InChI	GoogleScholar	UniChem		52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rat)	BDBM164066 (US9475819, 196 | US9062078, 196 | US9695183, 196 |...) Show SMILES Show InChI	GoogleScholar	UniChem		59	-9.16	n/a	n/a	n/a	n/a	n/a	n/a	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rat)	BDBM164066 (US9475819, 196 | US9062078, 196 | US9695183, 196 |...) Show SMILES Show InChI	GoogleScholar	UniChem		59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rat)	BDBM164066 (US9475819, 196 | US9062078, 196 | US9695183, 196 |...) Show SMILES Show InChI	GoogleScholar	UniChem		59	-10.4	n/a	n/a	n/a	n/a	n/a	n/a	40
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rat)	BDBM164066 (US9475819, 196 | US9062078, 196 | US9695183, 196 |...) Show SMILES Show InChI	GoogleScholar	UniChem		59	-9.16	n/a	n/a	n/a	n/a	n/a	n/a	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Human)	BDBM164066 (US9475819, 196 | US9062078, 196 | US9695183, 196 |...) Show SMILES Show InChI	GoogleScholar	UniChem		61	-9.14	n/a	n/a	n/a	n/a	n/a	n/a	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Human)	BDBM164066 (US9475819, 196 | US9062078, 196 | US9695183, 196 |...) Show SMILES Show InChI	GoogleScholar	UniChem		61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Human)	BDBM164066 (US9475819, 196 | US9062078, 196 | US9695183, 196 |...) Show SMILES Show InChI	GoogleScholar	UniChem		61	-9.14	n/a	n/a	n/a	n/a	n/a	n/a	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Human)	BDBM164066 (US9475819, 196 | US9062078, 196 | US9695183, 196 |...) Show SMILES Show InChI	GoogleScholar	UniChem		61	-9.14	n/a	n/a	n/a	n/a	n/a	n/a	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Human)	BDBM164066 (US9475819, 196 | US9062078, 196 | US9695183, 196 |...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Human)	BDBM164066 (US9475819, 196 | US9062078, 196 | US9695183, 196 |...) Show SMILES Show InChI	GoogleScholar	UniChem		1.50E+3	-8.34	n/a	n/a	n/a	n/a	n/a	n/a	40
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Human)	BDBM164066 (US9475819, 196 | US9062078, 196 | US9695183, 196 |...) Show SMILES Show InChI	GoogleScholar	UniChem		1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Human)	BDBM164066 (US9475819, 196 | US9062078, 196 | US9695183, 196 |...) Show SMILES Show InChI	GoogleScholar	UniChem		1.50E+3	-8.34	n/a	n/a	n/a	n/a	n/a	n/a	40
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Human)	BDBM164066 (US9475819, 196 | US9062078, 196 | US9695183, 196 |...) Show SMILES Show InChI	GoogleScholar	UniChem		1.50E+3	-8.34	n/a	n/a	n/a	n/a	n/a	n/a	40
TBA									Citation and Details
					More data for this Ligand-Target Pair