BDBM164137 US9062078, 267::US9475819, 267::US9637496, 267::US9695183, 267

SMILES: Fc1ccc(C(=O)N2C3CCC2C(C3)Nc2cnc(cn2)C(F)(F)F)c(c1)-c1ncccn1

InChI Key: InChIKey=FJQHMTUDGQPMMX-UHFFFAOYSA-N

Data: 12 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 164137   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin/Hypocretin receptor type 1 (Rat)	BDBM164137 (US9475819, 267 | US9062078, 267 | US9695183, 267 |...) Show SMILES Show InChI	GoogleScholar	UniChem		33	-9.48	n/a	n/a	n/a	n/a	n/a	n/a	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rat)	BDBM164137 (US9475819, 267 | US9062078, 267 | US9695183, 267 |...) Show SMILES Show InChI	GoogleScholar	UniChem		33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rat)	BDBM164137 (US9475819, 267 | US9062078, 267 | US9695183, 267 |...) Show SMILES Show InChI	GoogleScholar	UniChem		33	-10.7	n/a	n/a	n/a	n/a	n/a	n/a	40
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rat)	BDBM164137 (US9475819, 267 | US9062078, 267 | US9695183, 267 |...) Show SMILES Show InChI	GoogleScholar	UniChem		33	-9.48	n/a	n/a	n/a	n/a	n/a	n/a	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Human)	BDBM164137 (US9475819, 267 | US9062078, 267 | US9695183, 267 |...) Show SMILES Show InChI	GoogleScholar	UniChem		61	-9.14	n/a	n/a	n/a	n/a	n/a	n/a	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Human)	BDBM164137 (US9475819, 267 | US9062078, 267 | US9695183, 267 |...) Show SMILES Show InChI	GoogleScholar	UniChem		61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Human)	BDBM164137 (US9475819, 267 | US9062078, 267 | US9695183, 267 |...) Show SMILES Show InChI	GoogleScholar	UniChem		61	-9.14	n/a	n/a	n/a	n/a	n/a	n/a	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Human)	BDBM164137 (US9475819, 267 | US9062078, 267 | US9695183, 267 |...) Show SMILES Show InChI	GoogleScholar	UniChem		61	-9.14	n/a	n/a	n/a	n/a	n/a	n/a	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Human)	BDBM164137 (US9475819, 267 | US9062078, 267 | US9695183, 267 |...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70E+3	-8.26	n/a	n/a	n/a	n/a	n/a	n/a	40
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Human)	BDBM164137 (US9475819, 267 | US9062078, 267 | US9695183, 267 |...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Human)	BDBM164137 (US9475819, 267 | US9062078, 267 | US9695183, 267 |...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70E+3	-8.26	n/a	n/a	n/a	n/a	n/a	n/a	40
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Human)	BDBM164137 (US9475819, 267 | US9062078, 267 | US9695183, 267 |...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70E+3	-8.26	n/a	n/a	n/a	n/a	n/a	n/a	40
TBA									Citation and Details
					More data for this Ligand-Target Pair