BindingDB PrimarySearch_ki

Search and Browse
- Target
- Compound
- Special tools
- Citation
- Special Data Sets
- Other Databases
  - PDB 85% 100% Seq ID
  - UniProtKB/Swiss-Prot
  - UniProtKB/TrEMBL
  - PubMed
Download
- All Compounds & Data
- Target Names &
  - Ki IC50 Kd EC50
  - ΔG° ΔH° -TΔS°
Enter Data

BDBM185247 US10011588, Example 63::US10689373, Example 63::US9156829, 63

SMILES: FC(F)(F)c1cnc(N[C@H]2CCC[C@@H]2NC(=O)c2ncccc2C2CC2)cn1

InChI Key: InChIKey=AFBKMNNXFDRXES-UHFFFAOYSA-N

Data: 6 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 185247
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Orexin/Hypocretin receptor type 1 (Human)	BDBM185247 (US9156829, 63 \| US10011588, Example 63 \| US1068937...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Orexin receptor type 2 (Human)	BDBM185247 (US9156829, 63 \| US10011588, Example 63 \| US1068937...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Human)	BDBM185247 (US9156829, 63 \| US10011588, Example 63 \| US1068937...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	37
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Orexin receptor type 2 (Human)	BDBM185247 (US9156829, 63 \| US10011588, Example 63 \| US1068937...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	37
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Human)	BDBM185247 (US9156829, 63 \| US10011588, Example 63 \| US1068937...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Orexin receptor type 2 (Human)	BDBM185247 (US9156829, 63 \| US10011588, Example 63 \| US1068937...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair