BDBM19387 2,4-diaminopyrimidine derivative, 8c::6-[(benzyloxy)methyl]-5-(4-{[(4-methanesulfonylphenyl)methyl]amino}phenyl)pyrimidine-2,4-diamine::CHEMBL425594

SMILES CS(=O)(=O)c1ccc(CNc2ccc(cc2)-c2c(N)nc(N)nc2COCc2ccccc2)cc1

InChI Key InChIKey=AMXPCCCIUNIREO-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19387   

TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM19387(2,4-diaminopyrimidine derivative, 8c | 6-[(benzylo...)
Affinity DataIC50:  0.300nM EC50:  7.20nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM19387(2,4-diaminopyrimidine derivative, 8c | 6-[(benzylo...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM19387(2,4-diaminopyrimidine derivative, 8c | 6-[(benzylo...)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of human GHS receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed