BDBM19452 4-[2-phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]phenol::Pyrazolo[1,5-a]pyrimidine, 2a

SMILES Oc1ccc(cc1)-c1c(nn2c(cc(nc12)C(F)(F)F)C(F)(F)F)-c1ccccc1

InChI Key InChIKey=AEZPAUSGTAHLOQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 19452   

TargetEstrogen receptor beta(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign

LigandPNGBDBM19452(4-[2-phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a...)
Affinity DataKi:  139nM ΔG°:  -8.56kcal/molepH: 7.5 T: 2°CAssay Description:Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign

LigandPNGBDBM19452(4-[2-phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a...)
Affinity DataKi:  2.22E+3nM ΔG°:  -7.06kcal/molepH: 7.5 T: 2°CAssay Description:Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed