BDBM205144 2-({(3r,6r)-1-[(2-cyclopropyl- 4-methylphenyl)carbonyl]-6- methylpiperidin-3-yl}oxy)-3- methylpyridine-4-carbonitrile::US9546152, example 51

SMILES: C[C@@H]1CC[C@H](CN1C(=O)c1ccc(C)cc1C1CC1)Oc1nccc(C#N)c1C

InChI Key: InChIKey=AJNUFBMCWNNNIO-UHFFFAOYSA-N

Data: 2 KI  2 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 205144   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Human)	BDBM205144 (US9546152, example 51 | 2-({(3r,6r)-1-[(2-cyclopro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
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Orexin/Hypocretin receptor type 1 (Human)	BDBM205144 (US9546152, example 51 | 2-({(3r,6r)-1-[(2-cyclopro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Orexin receptor type 2 (Human)	BDBM205144 (US9546152, example 51 | 2-({(3r,6r)-1-[(2-cyclopro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Human)	BDBM205144 (US9546152, example 51 | 2-({(3r,6r)-1-[(2-cyclopro...) Show SMILES Show InChI	GoogleScholar	UniChem		443	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair