BDBM211259 US9247759, 10-7

SMILES COC(=O)c1cccc(CN2CC(=O)N(C2=O)c2cnn(Cc3c(C)noc3C)c2)c1

InChI Key InChIKey=BRVFGECVAWZHNJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 211259   

TargetTaste receptor type 2 member 8(Homo sapiens (Human))
Firmenich

Curated by ChEMBL
LigandPNGBDBM211259(US9247759, 10-7)
Affinity DataIC50:  100nMAssay Description:Antagonist activity at recombinant human TAS2R8 stably expressed in cells co-expressing Galpha16gust44 assessed as inhibition of andrographolide-indu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTaste receptor type 2 member 8(Homo sapiens (Human))
Firmenich

Curated by ChEMBL
LigandPNGBDBM211259(US9247759, 10-7)
Affinity DataIC50:  90nMAssay Description:In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent