BDBM211271 US9247759, 10-19

SMILES Cc1noc(C)c1Cn1cc(cn1)N1C(=O)CN(Cc2ccccc2C#N)C1=O

InChI Key InChIKey=CBCVXSCCJFRHQZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 211271   

TargetTaste receptor type 2 member 8(Homo sapiens (Human))
Firmenich

Curated by ChEMBL
LigandPNGBDBM211271(US9247759, 10-19)
Affinity DataIC50:  500nMAssay Description:Antagonist activity at recombinant human TAS2R8 stably expressed in cells co-expressing Galpha16gust44 assessed as inhibition of andrographolide-indu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTaste receptor type 2 member 8(Homo sapiens (Human))
Firmenich

Curated by ChEMBL
LigandPNGBDBM211271(US9247759, 10-19)
Affinity DataIC50:  500nMAssay Description:In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent