BDBM211305 US9247759, 10-53::US9247759, 10-88

SMILES Cc1noc(C)c1Cn1cc(cn1)N1C(=O)CN(Cc2ccccc2)C1=O

InChI Key InChIKey=AYGGIMJXTALZIK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 211305   

TargetTaste receptor type 2 member 8(Homo sapiens (Human))
Senomyx

US Patent
LigandPNGBDBM211305(US9247759, 10-53 | US9247759, 10-88)
Affinity DataIC50:  90nMAssay Description:In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTaste receptor type 2 member 8(Homo sapiens (Human))
Senomyx

US Patent
LigandPNGBDBM211305(US9247759, 10-53 | US9247759, 10-88)
Affinity DataIC50:  200nMAssay Description:Antagonist activity at recombinant human TAS2R8 stably expressed in cells co-expressing Galpha16gust44 assessed as inhibition of andrographolide-indu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTaste receptor type 2 member 8(Homo sapiens (Human))
Senomyx

US Patent
LigandPNGBDBM211305(US9247759, 10-53 | US9247759, 10-88)
Affinity DataIC50:  710nMAssay Description:In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent