BDBM21358 2-[1-({6-chloroimidazo[2,1-b][1,3]thiazole-5-}sulfonyl)-1H-indol-3-yl]ethan-1-amine::N1-(6-chloroimidazo[2,1-b][1,3]thiazole-5-sulfonyl)tryptamine::SAX-187::WAY-181187

SMILES: NCCc1cn(c2ccccc12)S(=O)(=O)c1c(Cl)nc2sccn12

InChI Key: InChIKey=RYBOXBBYCVOYNO-UHFFFAOYSA-N

Data: 10 KI  6 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 21358   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Human)	BDBM21358 (2-[1-({6-chloroimidazo[2,1-b][1,3]thiazole-5-}sulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6.5	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM21358 (2-[1-({6-chloroimidazo[2,1-b][1,3]thiazole-5-}sulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.49E+5	n/a	n/a	n/a	n/a	7.4	37
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Cytochrome P450 2A6 (Human)	BDBM21358 (2-[1-({6-chloroimidazo[2,1-b][1,3]thiazole-5-}sulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10E+4	n/a	n/a	n/a	n/a	7.4	37
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Cytochrome P450 2C19 (Human)	BDBM21358 (2-[1-({6-chloroimidazo[2,1-b][1,3]thiazole-5-}sulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.12E+5	n/a	n/a	n/a	n/a	7.4	37
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Cytochrome P450 2C9 (Human)	BDBM21358 (2-[1-({6-chloroimidazo[2,1-b][1,3]thiazole-5-}sulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	7.4	37
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Cytochrome P450 2D6 (Human)	BDBM21358 (2-[1-({6-chloroimidazo[2,1-b][1,3]thiazole-5-}sulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.96E+5	n/a	n/a	n/a	n/a	7.4	37
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Cytochrome P450 3A4 (Human)	BDBM21358 (2-[1-({6-chloroimidazo[2,1-b][1,3]thiazole-5-}sulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	7.4	37
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5-hydroxytryptamine receptor 6 (Human)	BDBM21358 (2-[1-({6-chloroimidazo[2,1-b][1,3]thiazole-5-}sulf...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 6 (Human)	BDBM21358 (2-[1-({6-chloroimidazo[2,1-b][1,3]thiazole-5-}sulf...) Show SMILES Show InChI	GoogleScholar	UniChem		2	-11.7	n/a	n/a	6.5	n/a	n/a	7.4	22
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5-hydroxytryptamine receptor 6 (Human)	BDBM21358 (2-[1-({6-chloroimidazo[2,1-b][1,3]thiazole-5-}sulf...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 6 (Human)	BDBM21358 (2-[1-({6-chloroimidazo[2,1-b][1,3]thiazole-5-}sulf...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Human)	BDBM21358 (2-[1-({6-chloroimidazo[2,1-b][1,3]thiazole-5-}sulf...) Show SMILES Show InChI	GoogleScholar	UniChem		2	-12.3	n/a	n/a	6.5	n/a	n/a	7.4	37
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Human)	BDBM21358 (2-[1-({6-chloroimidazo[2,1-b][1,3]thiazole-5-}sulf...) Show SMILES Show InChI	GoogleScholar	UniChem		2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Human)	BDBM21358 (2-[1-({6-chloroimidazo[2,1-b][1,3]thiazole-5-}sulf...) Show SMILES Show InChI	GoogleScholar	UniChem		2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Human)	BDBM21358 (2-[1-({6-chloroimidazo[2,1-b][1,3]thiazole-5-}sulf...) Show SMILES Show InChI	GoogleScholar	UniChem		124	-9.32	n/a	n/a	n/a	n/a	n/a	7.4	22
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5-hydroxytryptamine receptor 2B (Human)	BDBM21358 (2-[1-({6-chloroimidazo[2,1-b][1,3]thiazole-5-}sulf...) Show SMILES Show InChI	GoogleScholar	UniChem		458	-8.55	n/a	n/a	n/a	n/a	n/a	7.4	22
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5-hydroxytryptamine receptor 7 (Human)	BDBM21358 (2-[1-({6-chloroimidazo[2,1-b][1,3]thiazole-5-}sulf...) Show SMILES Show InChI	GoogleScholar	UniChem		679	-8.32	n/a	n/a	n/a	n/a	n/a	7.4	22
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