BDBM22753 1,2-bis(5-bromo-2-hydroxyphenyl)ethane-1,2-dione::Benzil-based compound, 31::cid_10662

SMILES Oc1ccc(Br)cc1C(=O)C(=O)c1cc(Br)ccc1O

InChI Key InChIKey=AAOYLOCWJSLLJU-UHFFFAOYSA-N

Data  5 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 22753   

TargetLiver carboxylesterase 1(Oryctolagus cuniculus (rabbit))
University Of Mississippi

LigandPNGBDBM22753(1,2-bis(5-bromo-2-hydroxyphenyl)ethane-1,2-dione |...)
Affinity DataKi:  53.5nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University Of Mississippi

LigandPNGBDBM22753(1,2-bis(5-bromo-2-hydroxyphenyl)ethane-1,2-dione |...)
Affinity DataKi:  72.7nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
University Of Mississippi

LigandPNGBDBM22753(1,2-bis(5-bromo-2-hydroxyphenyl)ethane-1,2-dione |...)
Affinity DataKi: >1.00E+5nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Mississippi

LigandPNGBDBM22753(1,2-bis(5-bromo-2-hydroxyphenyl)ethane-1,2-dione |...)
Affinity DataKi: >1.00E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Mississippi

LigandPNGBDBM22753(1,2-bis(5-bromo-2-hydroxyphenyl)ethane-1,2-dione |...)
Affinity DataKi: >1.00E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGalanin receptor type 3(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM22753(1,2-bis(5-bromo-2-hydroxyphenyl)ethane-1,2-dione |...)
Affinity DataIC50:  1.10E+3nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetRecBCD enzyme subunit RecD(Escherichia coli str. K-12 substr. MG1655)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM22753(1,2-bis(5-bromo-2-hydroxyphenyl)ethane-1,2-dione |...)
Affinity DataIC50: >1.19E+5nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay