BDBM22776 3,4,5,6-tetrachlorocyclohexa-3,5-diene-1,2-dione::Benzil-related compound, 55

SMILES ClC1=C(Cl)C(=O)C(=O)C(Cl)=C1Cl

InChI Key InChIKey=VRGCYEIGVVTZCC-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 22776   

TargetCoagulation factor XII(Homo sapiens (Human))
University of Mississippi

LigandPNGBDBM22776(3,4,5,6-tetrachlorocyclohexa-3,5-diene-1,2-dione |...)
Affinity DataKi:  875nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Oryctolagus cuniculus (rabbit))
University of Mississippi

LigandPNGBDBM22776(3,4,5,6-tetrachlorocyclohexa-3,5-diene-1,2-dione |...)
Affinity DataKi:  1.04E+3nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Mississippi

LigandPNGBDBM22776(3,4,5,6-tetrachlorocyclohexa-3,5-diene-1,2-dione |...)
Affinity DataKi:  1.67E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Mississippi

LigandPNGBDBM22776(3,4,5,6-tetrachlorocyclohexa-3,5-diene-1,2-dione |...)
Affinity DataKi:  3.20E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
University of Mississippi

LigandPNGBDBM22776(3,4,5,6-tetrachlorocyclohexa-3,5-diene-1,2-dione |...)
Affinity DataKi:  5.44E+3nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed