BDBM22881 5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine::Amthamine::CHEMBL554964

SMILES: Cc1c(sc(n1)N)CCN

InChI Key: InChIKey=LHVRFUVVRXGZPV-UHFFFAOYSA-N

Data: 3 KI  2 Kd  4 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 22881   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Human)	BDBM22881 (5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.58E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H2 receptor (Guinea pig)	BDBM22881 (5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	617	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H2 receptor (Guinea pig)	BDBM22881 (5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	191	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H2 receptor (Human)	BDBM22881 (5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	191	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H2 receptor (Rat)	BDBM22881 (5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.15E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H2 receptor (Guinea pig)	BDBM22881 (5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H4 receptor (Human)	BDBM22881 (5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		5.01E+3	-7.52	n/a	n/a	n/a	n/a	n/a	7.4	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H4 receptor (Human)	BDBM22881 (5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H2 receptor (Human)	BDBM22881 (5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		6.31E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair