BDBM230656 US9340517, 105

SMILES NC(=N)NCCC[C@H]1N[C@@H](CNC(=O)c2ccc3ccccc3c2)CCN(CC(c2ccccc2)c2ccccc2)C1=O

InChI Key InChIKey=DKFQXTHTGAKMJQ-XLJNKUFUSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 230656   

TargetMelanocortin receptor 5(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM230656(US9340517, 105)
Affinity DataIC50: <100nMpH: 7.4 T: 2°CAssay Description:Assessments of compound binding to human MC5R (hMC5R)) by displacement of an 125I-labeled NDP-MSH receptor ligand peptide were performed essentially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocortin receptor 5(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM230656(US9340517, 105)
Affinity DataIC50:  56nMpH: 7.4 T: 2°CAssay Description:Assessments of compound binding to human MC5R (hMC5R)) by displacement of an 125I-labeled NDP-MSH receptor ligand peptide were performed essentially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocortin receptor 5(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM230656(US9340517, 105)
Affinity DataIC50:  57nMpH: 7.4 T: 2°CAssay Description:Assessments of compound binding to human MC5R (hMC5R)) by displacement of an 125I-labeled NDP-MSH receptor ligand peptide were performed essentially ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM230656(US9340517, 105)
Affinity DataIC50:  3.28E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were carried out using commercial or in-house prepared hMC1R, hMC3R and hMC4R membranes and [125I] NDP-MSH, as per the hMC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocortin receptor 5(Macaca fascicularis (Cynomolgus monkey))
Mimetica

US Patent
LigandPNGBDBM230656(US9340517, 105)
Affinity DataIC50:  6.03E+3nMAssay Description:Radioligand binding and cAMP assays were also conducted using membranes and cells expressing MC5R cloned from other species (mouse MC5R membranes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM230656(US9340517, 105)
Affinity DataIC50:  6.66E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were carried out using commercial or in-house prepared hMC1R, hMC3R and hMC4R membranes and [125I] NDP-MSH, as per the hMC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocortin receptor 3(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM230656(US9340517, 105)
Affinity DataIC50:  1.75E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were carried out using commercial or in-house prepared hMC1R, hMC3R and hMC4R membranes and [125I] NDP-MSH, as per the hMC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocortin receptor 5(Mus musculus (Mouse))
Mimetica

US Patent
LigandPNGBDBM230656(US9340517, 105)
Affinity DataIC50:  4.00E+3nMAssay Description:Radioligand binding and cAMP assays were also conducted using membranes and cells expressing MC5R cloned from other species (mouse MC5R membranes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent