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BDBM243806 US9428456, 2.009

SMILES: CCN(CC)C(=O)C1CCN(Cc2cccc(NC(=O)c3ccc(Cl)cc3)c2)CC1

InChI Key: InChIKey=AOCGNIQLFQCHQE-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 243806   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-X-C chemokine receptor type 7 (CXCR7)


(Homo sapiens (Human))
BDBM243806
PNG
(US9428456, 2.009)
Show SMILES CCN(CC)C(=O)C1CCN(Cc2cccc(NC(=O)c3ccc(Cl)cc3)c2)CC1
Show InChI InChI=1S/C24H30ClN3O2/c1-3-28(4-2)24(30)20-12-14-27(15-13-20)17-18-6-5-7-22(16-18)26-23(29)19-8-10-21(25)11-9-19/h5-11,16,20H,3-4,12-15,17H2,1-2H3,(H,26,29)
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1n/an/an/a37



ACTELION PHARMACEUTICALS LTD

US Patent


Assay Description
CHO-K1 CXCR7 b-arrestin cells are detached from culture dishes with a cell dissociation buffer (Invitrogen, #13151-014) and collected in growing medi...


US Patent US9428456 (2016)


BindingDB Entry DOI: 10.7270/Q29022PZ
More data for this
Ligand-Target Pair